General Information
SPKB ID SPKB06099
Signal sequence MGPVRLGILLFLFLAVHEAWA
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06099.cif
Physicochemical Information
Molecular weight 2353.89684
Aliphatic index 153.3333333
Isoelectric point 7.551312718
Charge (pH=7) 0.090665202
Topological polar surface area 780.2
Aromaticity 0.142857143
Average rotatable bonds 3.428571429
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 26
X logP energy 0.56797
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
