General Information
SPKB ID SPKB06098
Signal sequence MAALAPVGSPASRGPRLAAGLRLLPMLGLLQLLAEPGLG
Length 39
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..39
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06098.cif
Physicochemical Information
Molecular weight 3849.69804
Aliphatic index 135.3846154
Isoelectric point 12.19913393
Charge (pH=7) 1.999749488
Topological polar surface area 1431.72
Aromaticity 0
Average rotatable bonds 3.102564103
Number of hydrogen bond donors 48
Number of hydrogen bond acceptors 49
X logP energy -11.14659
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
