General Information
SPKB ID SPKB06097
Signal sequence MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHG
Length 31
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..31
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9C7U,
Predicted Structure ID SPKB06097.cif
Physicochemical Information
Molecular weight 2825.40564
Aliphatic index 147.7419355
Isoelectric point 7.550323994
Charge (pH=7) 0.08889339
Topological polar surface area 1030.97
Aromaticity 0
Average rotatable bonds 2.806451613
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 37
X logP energy -8.9559
Hydropathy
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,