Peptide-Information

General Information

SPKB ID SPKB06095

Signal sequence MDARWWAVVVLAAFPSLGAG

Length 20

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..20

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06095.cif

Structure SPKB06095.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2117.49624

Aliphatic index 107.5

Isoelectric point 6.338718596

Charge (pH=7) -0.001572528

Topological polar surface area 758.44

Aromaticity 0.15

Average rotatable bonds 3.05

Number of hydrogen bond donors 27

Number of hydrogen bond acceptors 25

X logP energy -3.28773

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,