General Information
SPKB ID SPKB06093
Signal sequence MRKVVLITGASSGIGLALCKRL
Length 22
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06093.cif
Physicochemical Information
Molecular weight 2286.86624
Aliphatic index 141.8181818
Isoelectric point 11.65159386
Charge (pH=7) 3.935412893
Topological polar surface area 910.95
Aromaticity 0
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 32
X logP energy -8.06546
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
