General Information
SPKB ID SPKB06092
Signal sequence MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTA
Length 44
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..44
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06092.cif
Physicochemical Information
Molecular weight 4731.64864
Aliphatic index 102.0454545
Isoelectric point 12.02327059
Charge (pH=7) 2.937771461
Topological polar surface area 1699.65
Aromaticity 0.113636364
Average rotatable bonds 3.181818182
Number of hydrogen bond donors 62
Number of hydrogen bond acceptors 56
X logP energy -9.49082
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
