General Information
SPKB ID SPKB06091
Signal sequence MAGKRSGWSRAALLQLLLGVNLVVMPPTRA
Length 30
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06091.cif
Physicochemical Information
Molecular weight 3206.90474
Aliphatic index 120.3333333
Isoelectric point 12.80742779
Charge (pH=7) 3.997679332
Topological polar surface area 1264.02
Aromaticity 0.033333333
Average rotatable bonds 3.466666667
Number of hydrogen bond donors 45
Number of hydrogen bond acceptors 42
X logP energy -10.65639
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
