Peptide-Information

General Information

SPKB ID SPKB06090

Signal sequence MVLLRVLILLLSWAAGMG

Length 18

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..18

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06090.cif

Structure SPKB06090.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 1956.52174

Aliphatic index 195

Isoelectric point 10.55000222

Charge (pH=7) 0.997980988

Topological polar surface area 655.94

Aromaticity 0.055555556

Average rotatable bonds 3.555555556

Number of hydrogen bond donors 24

Number of hydrogen bond acceptors 23

X logP energy 0.06297

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,