General Information
SPKB ID SPKB06088
Signal sequence MRVRIGLTLLLCAVLLSLASA
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06088.cif
Physicochemical Information
Molecular weight 2213.81184
Aliphatic index 190.4761905
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 829.81
Aromaticity 0
Average rotatable bonds 3.523809524
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 29
X logP energy -4.95896
Hydropathy
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,