General Information
SPKB ID SPKB06086
Signal sequence MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLA
Length 33
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..33
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06086.cif
Physicochemical Information
Molecular weight 3524.19114
Aliphatic index 121.2121212
Isoelectric point 12.50005466
Charge (pH=7) 2.998417538
Topological polar surface area 1433.29
Aromaticity 0.060606061
Average rotatable bonds 3.454545455
Number of hydrogen bond donors 52
Number of hydrogen bond acceptors 45
X logP energy -12.52372
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
