General Information
SPKB ID SPKB06085
Signal sequence MKVHMHTKFCLICLLTFIFHHCNHC
Length 25
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06085.cif
Physicochemical Information
Molecular weight 3057.78274
Aliphatic index 89.6
Isoelectric point 8.365152038
Charge (pH=7) 2.204040823
Topological polar surface area 1040.71
Aromaticity 0.12
Average rotatable bonds 3.92
Number of hydrogen bond donors 40
Number of hydrogen bond acceptors 42
X logP energy -4.4025
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
