General Information
SPKB ID SPKB06084
Signal sequence MGLQACLLGLFALILSGKCSY
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 3EE6,
Predicted Structure ID SPKB06084.cif
Physicochemical Information
Molecular weight 2201.72834
Aliphatic index 139.5238095
Isoelectric point 8.221165971
Charge (pH=7) 0.872889419
Topological polar surface area 775.12
Aromaticity 0.095238095
Average rotatable bonds 3.476190476
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 30
X logP energy -4.4662
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
