General Information
SPKB ID SPKB06083
Signal sequence MVGPAPRRRLRPLAALALVLALAPGLPTARA
Length 31
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..31
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06083.cif
Physicochemical Information
Molecular weight 3189.94914
Aliphatic index 132.5806452
Isoelectric point 13.10207708
Charge (pH=7) 4.997967743
Topological polar surface area 1222.1
Aromaticity 0
Average rotatable bonds 3.096774194
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 39
X logP energy -9.01975
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
