General Information
SPKB ID SPKB06082
Signal sequence MGPGPRLLLPLVLCVGLGALVFSSGAEG
Length 28
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06082.cif
Physicochemical Information
Molecular weight 2724.31534
Aliphatic index 135.7142857
Isoelectric point 6.232433001
Charge (pH=7) -0.062218605
Topological polar surface area 962.31
Aromaticity 0.035714286
Average rotatable bonds 3
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 35
X logP energy -6.83633
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
