General Information
SPKB ID SPKB06081
Signal sequence MLRGPGPGLLLLAVQCLGTAVPSTGA
Length 26
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06081.cif
Physicochemical Information
Molecular weight 2493.02084
Aliphatic index 123.8461538
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 930.13
Aromaticity 0
Average rotatable bonds 2.923076923
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 34
X logP energy -9.19223
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
