Peptide-Information

General Information

SPKB ID SPKB06080

Signal sequence MALWRGSAYAGFLALAVGCVFL

Length 22

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..22

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06080.cif

Structure SPKB06080.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2316.80724

Aliphatic index 120

Isoelectric point 8.527213491

Charge (pH=7) 0.935155858

Topological polar surface area 792.57

Aromaticity 0.181818182

Average rotatable bonds 3.181818182

Number of hydrogen bond donors 30

Number of hydrogen bond acceptors 28

X logP energy -2.83463

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,