Peptide-Information

General Information

SPKB ID SPKB06079

Signal sequence MGRAGAAAVIPGLALLWAVGLGSA

Length 24

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..24

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06079.cif

Structure SPKB06079.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2222.67674

Aliphatic index 134.5833333

Isoelectric point 10.55000222

Charge (pH=7) 0.997980988

Topological polar surface area 821.75

Aromaticity 0.041666667

Average rotatable bonds 2.833333333

Number of hydrogen bond donors 29

Number of hydrogen bond acceptors 28

X logP energy -6.37363

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,