General Information
SPKB ID SPKB06078
Signal sequence MAARWRFWCVSVTMVVALLIVCDVPSASA
Length 29
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6S7T,
Predicted Structure ID SPKB06078.cif
Physicochemical Information
Molecular weight 3182.86884
Aliphatic index 117.5862069
Isoelectric point 8.231404231
Charge (pH=7) 0.874474729
Topological polar surface area 1142.93
Aromaticity 0.103448276
Average rotatable bonds 3.310344828
Number of hydrogen bond donors 44
Number of hydrogen bond acceptors 41
X logP energy -6.93186
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
