General Information
SPKB ID SPKB06077
Signal sequence MGDKIWLPFPVLLLAALPPVLLPGAAG
Length 27
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06077.cif
Physicochemical Information
Molecular weight 2770.45514
Aliphatic index 151.8518519
Isoelectric point 6.337367167
Charge (pH=7) -0.00186425
Topological polar surface area 855.08
Aromaticity 0.074074074
Average rotatable bonds 2.925925926
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 31
X logP energy 0.5122
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
