General Information
SPKB ID SPKB06076
Signal sequence MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGG
Length 41
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..41
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06076.cif
Physicochemical Information
Molecular weight 4483.41444
Aliphatic index 111.9512195
Isoelectric point 12.62573447
Charge (pH=7) 6.93513599
Topological polar surface area 1801.35
Aromaticity 0.073170732
Average rotatable bonds 3.585365854
Number of hydrogen bond donors 67
Number of hydrogen bond acceptors 57
X logP energy -15.84861
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
