General Information
SPKB ID SPKB06075
Signal sequence MKLHYVAVLTLAILMFLTWLPESLS
Length 25
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06075.cif
Physicochemical Information
Molecular weight 2890.57824
Aliphatic index 156
Isoelectric point 7.541810143
Charge (pH=7) 0.089523065
Topological polar surface area 961.87
Aromaticity 0.12
Average rotatable bonds 3.64
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 36
X logP energy -0.6127
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
