General Information
SPKB ID SPKB06074
Signal sequence MEAVAVAAAVGVLLLAGAGGAAG
Length 23
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06074.cif
Physicochemical Information
Molecular weight 1939.30064
Aliphatic index 140.4347826
Isoelectric point 3.849983241
Charge (pH=7) -1.000240578
Topological polar surface area 740.82
Aromaticity 0
Average rotatable bonds 2.652173913
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -7.2198
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
