Peptide-Information

General Information

SPKB ID SPKB06073

Signal sequence MSSRIARALALVVTLLHLTRLALS

Length 24

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..24

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06073.cif

Structure SPKB06073.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2606.21184

Aliphatic index 170.8333333

Isoelectric point 12.80107132

Charge (pH=7) 3.088883456

Topological polar surface area 1048.15

Aromaticity 0

Average rotatable bonds 3.625

Number of hydrogen bond donors 40

Number of hydrogen bond acceptors 35

X logP energy -8.44369

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,