Peptide-Information

General Information

SPKB ID SPKB06072

Signal sequence MAMGLFRVCLVVVTA

Length 15

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..15

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06072.cif

Structure SPKB06072.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 1610.06714

Aliphatic index 142.6666667

Isoelectric point 8.549912035

Charge (pH=7) 0.936006272

Topological polar surface area 552.85

Aromaticity 0.066666667

Average rotatable bonds 3.4

Number of hydrogen bond donors 21

Number of hydrogen bond acceptors 21

X logP energy -2.10433

Hydropathy

Literature Information

Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Publication Year 2018

PubMed ID 30217974,

Patent ID NA,