General Information
SPKB ID SPKB06071
Signal sequence MATAERRALGIGFQWLSLATLVLICAG
Length 27
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06071.cif
Physicochemical Information
Molecular weight 2862.44414
Aliphatic index 130.3703704
Isoelectric point 8.549845238
Charge (pH=7) 0.937778084
Topological polar surface area 1100.59
Aromaticity 0.074074074
Average rotatable bonds 3.444444444
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 37
X logP energy -7.96416
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
