General Information
SPKB ID SPKB06070
Signal sequence MPGRAPLRTVPGALGAWLLGGLWAWTLCGLCSLGAVG
Length 37
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..37
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06070.cif
Physicochemical Information
Molecular weight 3722.48814
Aliphatic index 113.5135135
Isoelectric point 8.834915637
Charge (pH=7) 1.874028245
Topological polar surface area 1316.41
Aromaticity 0.081081081
Average rotatable bonds 2.972972973
Number of hydrogen bond donors 49
Number of hydrogen bond acceptors 46
X logP energy -8.73366
Hydropathy 
Literature Information
Title Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import
DOI 10.1038/s41467-018-06188-z,
Publication Year 2018
PubMed ID 30217974,
Patent ID NA,
