SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06068

Signal sequence   MAKFFLTAAFAAAALA

Length  16

Organism  Humicola insolens

UniProt ID  Q9C1S9,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06068.cif

Structure  SPKB06068.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1614.96604

Aliphatic index  98.75

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  546.07

Aromaticity  0.1875

Average rotatable bonds  3.0625

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  -2.0873

Hydropathy 



Literature Information


Title  In silico and in vivo analysis of signal peptides effect on recombinant glucose oxidase production in nonconventional yeast Yarrowia lipolytica

DOI  10.1007/s11274-018-2512-x,

Publication Year  2018

PubMed ID  30083963,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.