SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06063

Signal sequence   MKLTKLVALAGAALA

Length  15

Organism  Yarrowia lipolytica

UniProt ID  Q12725,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06063.cif

Structure  SPKB06063.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1470.87724

Aliphatic index  156.6666667

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  542.99

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  -2.8513

Hydropathy 



Literature Information


Title  In silico and in vivo analysis of signal peptides effect on recombinant glucose oxidase production in nonconventional yeast Yarrowia lipolytica

DOI  10.1007/s11274-018-2512-x,

Publication Year  2018

PubMed ID  30083963,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.