SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06060

Signal sequence   MKLSTILFTACATLAAALPSPITPSEA

Length  27

Organism  Yarrowia lipolytica

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06060.cif

Structure  SPKB06060.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2719.24714

Aliphatic index  108.8888889

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  998.48

Aromaticity  0.037037037

Average rotatable bonds  3.037037037

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  39

X logP energy  -9.6628

Hydropathy 



Literature Information


Title  In silico and in vivo analysis of signal peptides effect on recombinant glucose oxidase production in nonconventional yeast Yarrowia lipolytica

DOI  10.1007/s11274-018-2512-x,

Publication Year  2018

PubMed ID  30083963,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.