SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06058

Signal sequence   MQTLLVSSLVVSLAAALPHYIR

Length  22

Organism  Aspergillus niger

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06058.cif

Structure  SPKB06058.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2382.89014

Aliphatic index  159.5454545

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  900.45

Aromaticity  0.045454545

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -6.05673

Hydropathy 



Literature Information


Title  In silico and in vivo analysis of signal peptides effect on recombinant glucose oxidase production in nonconventional yeast Yarrowia lipolytica

DOI  10.1007/s11274-018-2512-x,

Publication Year  2018

PubMed ID  30083963,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.