Peptide-Information

General Information

SPKB ID SPKB06057

Signal sequence MSVPTQVLGLLLLWLTDARC

Length 20

Organism Mus musculus (Mouse)

UniProt ID NA,

Motif 1..20

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 8TCO,

Predicted Structure ID SPKB06057.cif

Structure SPKB06057.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2229.72404

Aliphatic index 151

Isoelectric point 6.161167719

Charge (pH=7) -0.063547244

Topological polar surface area 826.2

Aromaticity 0.05

Average rotatable bonds 3.5

Number of hydrogen bond donors 30

Number of hydrogen bond acceptors 29

X logP energy -4.48013

Hydropathy

Literature Information

Title Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR

Publication Year 2018

PubMed ID 29740673,

Patent ID NA,