General Information
SPKB ID SPKB06056
Signal sequence MGRLTSSFLLLIVPAYVLS
Length 19
Organism Mus musculus (Mouse)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06056.cif
Physicochemical Information
Molecular weight 2080.55664
Aliphatic index 158.9473684
Isoelectric point 9.348807885
Charge (pH=7) 0.997130574
Topological polar surface area 741.38
Aromaticity 0.105263158
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 27
X logP energy -3.56413
Hydropathy 
Literature Information
Title Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR
DOI 10.1007/s00253-018-8986-5,
Publication Year 2018
PubMed ID 29740673,
Patent ID NA,
