General Information
SPKB ID SPKB06055
Signal sequence MKWVTFISLLFLFASAYS
Length 18
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06055.cif
Physicochemical Information
Molecular weight 2124.56844
Aliphatic index 113.8888889
Isoelectric point 9.298300651
Charge (pH=7) 0.996838851
Topological polar surface area 700.98
Aromaticity 0.277777778
Average rotatable bonds 3.611111111
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -0.8397
Hydropathy 
Literature Information
Title Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR
DOI 10.1007/s00253-018-8986-5,
Publication Year 2018
PubMed ID 29740673,
Patent ID NA,
