SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06051

Signal sequence   MKLSTILFTACATLALALA

Length  19

Organism  Yarrowia lipolytica

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06051.cif

Structure  SPKB06051.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1952.44124

Aliphatic index  149.4736842

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  694.06

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.3099

Hydropathy 



Literature Information


Title  Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags

DOI  10.1007/s00253-018-8966-9,

Publication Year  2018

PubMed ID  29704042,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.