SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06047

Signal sequence   MFKKRWVLIVCIIFTSGLFWTFWSVTA

Length  27

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06047.cif

Structure  SPKB06047.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3281.02554

Aliphatic index  108.148148148148

Isoelectric point  10.7931983293965

Charge (pH=7)   2.93541620446313

Topological polar surface area  1082.38

Aromaticity  0.259259259259259

Average rotatable bonds  3.74074074074074

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  38

X logP energy  -0.673129999999895

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.