General Information
SPKB ID SPKB06043
Signal sequence GWSCIILFLVATATGVHSQ
Length 19
Organism Komagataella phaffii
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6DWI,
Predicted Structure ID SPKB06043.cif
Physicochemical Information
Molecular weight 2003.34644
Aliphatic index 123.1578947
Isoelectric point 7.35902981
Charge (pH=7) 0.026918674
Topological polar surface area 755.6
Aromaticity 0.105263158
Average rotatable bonds 3.210526316
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 27
X logP energy -6.2023
Hydropathy 
Literature Information
Title A systematic analysis of the expression of the anti-HIV VRC01 antibody in Pichia pastoris through signal peptide optimization
DOI 10.1016/j.pep.2018.03.013,
Publication Year 2018
PubMed ID 29601964,
Patent ID NA,
