SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06042

Signal sequence   MRGIIAAYTSATLLALLLVTWLTHSSA

Length  27

Organism  Chlamydomonas reinhardtii

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06042.cif

Structure  SPKB06042.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2874.43434

Aliphatic index  144.8148148

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  1088.13

Aromaticity  0.074074074

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -8.08663

Hydropathy 



Literature Information


Title  Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii

DOI  10.1371/journal.pone.0192433,

Publication Year  2018

PubMed ID  29408937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.