SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06041

Signal sequence   MMSSLISSRVAALLPALQHASG

Length  22

Organism  Chlamydomonas reinhardtii

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06041.cif

Structure  SPKB06041.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2240.66414

Aliphatic index  120

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  900.45

Aromaticity  0

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -10.35493

Hydropathy 



Literature Information


Title  Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii

DOI  10.1371/journal.pone.0192433,

Publication Year  2018

PubMed ID  29408937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.