SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06037

Signal sequence   MRRAIALGVGLALLGLLLPGSLA

Length  23

Organism  Chlamydomonas reinhardtii

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06037.cif

Structure  SPKB06037.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2275.86774

Aliphatic index  182.6086957

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  838.76

Aromaticity  0

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  28

X logP energy  -4.48186

Hydropathy 



Literature Information


Title  Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii

DOI  10.1371/journal.pone.0192433,

Publication Year  2018

PubMed ID  29408937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.