SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06035

Signal sequence   MARTGALLLVALALAGCAQA

Length  20

Organism  Chlamydomonas reinhardtii

UniProt ID  P20507,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3B1B,

Predicted Structure ID  SPKB06035.cif

Structure  SPKB06035.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1914.35494

Aliphatic index  147

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  741.44

Aromaticity  0

Average rotatable bonds  3.1

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -6.50943

Hydropathy 



Literature Information


Title  Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii

DOI  10.1371/journal.pone.0192433,

Publication Year  2018

PubMed ID  29408937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.