SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06033

Signal sequence   MAQWKAAVLLLALACASY

Length  18

Organism  Chlamydomonas reinhardtii

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06033.cif

Structure  SPKB06033.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1923.36184

Aliphatic index  136.1111111

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  683.38

Aromaticity  0.111111111

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -2.6583

Hydropathy 



Literature Information


Title  Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii

DOI  10.1371/journal.pone.0192433,

Publication Year  2018

PubMed ID  29408937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.