General Information
SPKB ID SPKB06030
Signal sequence MRLLPLLALL
Length 10
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..10
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06030.cif
Physicochemical Information
Molecular weight 1152.54724
Aliphatic index 244
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 378.33
Aromaticity 0
Average rotatable bonds 3.7
Number of hydrogen bond donors 13
Number of hydrogen bond acceptors 13
X logP energy 1.58057
Hydropathy 
Literature Information
Title Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes
DOI 10.2337/db17-0021,
Publication Year 2018
PubMed ID 29343547,
Patent ID NA,
