SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06028

Signal sequence   ALLVTFLAGCQA

Length  12

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..12



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06028.cif

Structure  SPKB06028.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1206.46554

Aliphatic index  146.6666667

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  446.74

Aromaticity  0.083333333

Average rotatable bonds  3.083333333

Number of hydrogen bond donors  16

Number of hydrogen bond acceptors  16

X logP energy  -2.9647

Hydropathy 



Literature Information


Title  DeepSig: deep learning improves signal peptide detection in proteins

DOI  10.1093/bioinformatics/btx818,

Publication Year  2018

PubMed ID  29280997,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.