SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06024

Signal sequence   MSLSRRQFIQASGIALCAGAVPLKASA

Length  27

Organism  Escherichia coli

UniProt ID  P26648,

Motif  1..27



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Cytoplasmic membrane

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06024.cif

Structure  SPKB06024.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2747.26944

Aliphatic index  105.1851852

Isoelectric point  11.48119255

Charge (pH=7)   2.935707927

Topological polar surface area  1128.05

Aromaticity  0.037037037

Average rotatable bonds  3.37037037

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -13.14066

Hydropathy 



Literature Information


Title  Signal Peptide Hydrophobicity Modulates Interaction with the Twin-Arginine Translocase

DOI  10.1128/mBio.00909-17,

Publication Year  2017

PubMed ID  28765221,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.