General Information
SPKB ID SPKB06023
Signal sequence MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYY
Length 40
Organism Human immunodeficiency virus type 1
UniProt ID NA,
Motif 1..40
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4R4H,
Predicted Structure ID SPKB06023.cif
Physicochemical Information
Molecular weight 5052.08824
Aliphatic index 82.75
Isoelectric point 10.11563706
Charge (pH=7) 4.027022642
Topological polar surface area 1828.91
Aromaticity 0.2
Average rotatable bonds 4.05
Number of hydrogen bond donors 70
Number of hydrogen bond acceptors 63
X logP energy -4.85629
Hydropathy 
Literature Information
Title Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide
DOI 10.7554/eLife.26067,
Publication Year 2017
PubMed ID 28753126,
Patent ID NA,
