SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06021

Signal sequence   MKYLLPWLALAGLVLAQPAMA

Length  21

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06021.cif

Structure  SPKB06021.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2270.86274

Aliphatic index  149.047619

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  732.87

Aromaticity  0.095238095

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  27

X logP energy  0.3432

Hydropathy 



Literature Information


Title  Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxin(H35L) in Escherichia coli

DOI  10.1186/s13568-017-0394-1,

Publication Year  2017

PubMed ID  28497288,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.