SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06018

Signal sequence   MKKITAAAGLLLLAAFSASA

Length  20

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06018.cif

Structure  SPKB06018.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1948.39464

Aliphatic index  132.5

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  728.95

Aromaticity  0.05

Average rotatable bonds  3.25

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -5.7701

Hydropathy 



Literature Information


Title  Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxin(H35L) in Escherichia coli

DOI  10.1186/s13568-017-0394-1,

Publication Year  2017

PubMed ID  28497288,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.