SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06016

Signal sequence   MKTHIVSSVTTTLLLGSILMNPVANA

Length  26

Organism  Staphylococcus aureus

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06016.cif

Structure  SPKB06016.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2712.25864

Aliphatic index  131.1538462

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  1064.52

Aromaticity  0

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  40

X logP energy  -11.2078

Hydropathy 



Literature Information


Title  Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxin(H35L) in Escherichia coli

DOI  10.1186/s13568-017-0394-1,

Publication Year  2017

PubMed ID  28497288,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.