General Information
SPKB ID SPKB06014
Signal sequence MKKIWLALAGLVLAFSASA
Length 19
Organism Escherichia coli
UniProt ID NA,
Motif 1..19
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8XFP,
Predicted Structure ID SPKB06014.cif
Physicochemical Information
Molecular weight 1990.47774
Aliphatic index 144.2105263
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 695.41
Aromaticity 0.105263158
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -2.2955
Hydropathy
Literature Information
Title Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxin(H35L) in Escherichia coli
DOI 10.1186/s13568-017-0394-1,
Publication Year 2017
PubMed ID 28497288,
Patent ID NA,