SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06007

Signal sequence   MKKIIICVILLAIMLLAA

Length  18

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cytoplasmic membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06007.cif

Structure  SPKB06007.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1970.69104

Aliphatic index  227.7777778

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  610.06

Aromaticity  0

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  2.4645

Hydropathy 



Literature Information


Title  In vivo analysis of sequence requirements for processing and degradation of the colicin A lysis protein signal peptide

DOI  10.1128/JB.180.12.3026-3030.1998,

Publication Year  1998

PubMed ID  9620949,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.